Home About us MoEF Contact us Sitemap Tamil Website  
About Envis
Whats New
Research on Microbes
Microbiology Experts
Online Submission
Access Statistics

Site Visitors

blog tracking

International Journal of Biological Macromolecules
Vol. 107, 2018, Pages: 585-594

Pyrazole-based compounds in chitosan liposomal emulsion for antimicrobial cotton fabrics

Ahmed Nada, Marwa Al-Moghazy, Ahmed A.F.Soliman, Gehan M.T.Rashwan, Taghreed Hosny Ahmed Eldawy, Ashraf Abd Elhakim Hassan, Galal Hosni Sayed

Pretreatment & Finishing of Cellulose Based Textiles Dept., Textile Research Division, National Research Centre, Dokki, Giza, Egypt.


The chemistry of pyrazoles has gained increasing attention due to its diverse pharmacological properties such as antiviral, antagonist, antimicrobial, anticancer, anti-inflammatory, analgesic, anti-prostate cancer, herbicidal, acaricidal and insecticidal activities. 1-Phenyl pyrazole-3, 5-diamine, 4-[2-(4-methylphenyl) diazenyl] and 1H- pyrazole-3 (1), 5-diamine, 4-[2-(4-methylphenyl) diazenyl] (2) were synthesized, characterized and encapsulated into liposomal chitosan emulsions for textile finishing. The chemical modifications of cotton fabrics were demonstrated by infrared analysis. Retention of the fabric mechanical properties was investigated by reporting the tensile strength values. Synthesized pyrazole-based compounds were screened for cytotoxicity against skin fibroblast cell line and showed very limited toxicity for both compounds. Antimicrobial potentials of the treated cotton fabrics were tested against bacterial strains E. coli ATCC 8379 and Staphylococcus aureus ATCC 25923.

Keywords: Lecithin, Emulsion, Cotton fabric, Wet process, Pharmacological.

Copyright © 2005 ENVIS Centre ! All rights reserved
This site is optimized for 1024 x 768 screen resolution