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Arabian Journal of Chemistry
Volume 15 (3), 2022, 103688

Bioprospecting Dodonaea viscosa Jacq.; a traditional medicinal plant for antioxidant, cytotoxic, antidiabetic and antimicrobial potential

Marya Nawaz Malika, Ihsan-ul Haqb

Department of Pharmacy, Faculty of Biological Sciences, Quaid-i-Azam University, Islamabad 45320, Pakistan.

Abstract

Dodonaea viscosa Jacq. is an ethnomedicinal plant that has been extensively used for the treatment of gout, rheumatism and pain. Current study was undertaken to mine its antioxidant, antimicrobial, cytotoxic and antidiabetic potential. Chromogenic assays were employed to establish plant’s multimode antioxidant profile whereas HPLC fingerprinting was performed to quantify polyphenols. Standard brine shrimp lethality, MTT and SRB assays proved its cytotoxicity potential.

Keywords: Dodonaea viscosa, Phytoconstituents, Secondary metabolites, Hep G2 hepatoma cell line, THP-1 human leukemia cell linea-Amylase inhibition, Antiproliferative activity.

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