of worldwide distributed carbohydrate-related
digital resources: online connection of the Bacterial
Carbohydrate Structure DataBase and GLYCOSCIENCES.de
Philip Toukach, Hiren J Joshi1, Rene´
Ranzinger1, Yuri Knirel and Claus-W. von der Lieth1,*
N. D. Zelinsky Institute of Organic Chemistry, Russian Academy
of Sciences, 119991 Moscow, Russia and 1German
Cancer Research Center, Spectroscopic Department (B090), Molecular
Modeling, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany.
Functional glycomics, the scientific attempt
to identify and assign functions to all glycan molecules
synthesized by an organism, is an emerging field of science.
In recent years, several databases have been started, all
aiming to support deciphering the biological function of
carbohydrates. However, diverse encoding and storage schemes
are in use amongst these databases, significantly hampering
the interchange of data. The mutual online access between
the Bacterial Carbohydrate Structure DataBase (BCSDB) and
the GLYCOSCIENCES.de portal, as a first reported attempt
of a structurebased direct interconnection of two glyco-related
databases is described. In this approach, users have to
learn only one interface, will always have access to the
latest data of both services, and will have the results
of both searches presented in a consistent way. The establishment
of this connection helped to find shortcomings and inconsistencies
in the database design and functionality related to underlying
data concepts and structural representations. For the maintenance
of the databases, duplication of work can be easily avoided,
and will hopefully lead to a better worldwide acceptance
of both services within the community of glycoscienists.
DataBase;GLYCOSCIENCES.de portal;GlycoSuiteDB;glycan molecules;taxonomy.
Corresponding author: Tel +49 6221 424541;
Fax +49 6221 42454.