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CLINICAL MICROBIOLOGY REVIEWS
Vol. 19, No. 2, 2006, Pages: 259–282


Clinical and Laboratory Features of the Nocardia spp.
Based on Current Molecular Taxonomy

Barbara A. Brown-Elliott,1 June M. Brown,2 Patricia S. Conville,3 and Richard J. Wallace, Jr.1*

The University of Texas Health Center, Department of Microbiology, 11937 U.S. Highway 271,
Tyler, TX 75708.

Abstract

Although some, controversy exists concerning the specific number of valid species of Nocardia, the genus Nocardia currently contains more than 50 species that have been characterizedby phenotypic and molecular methods (Tables 1 and 2) (56). However, not all of thesespecies have been subjected to the same level of analysis. Further work may reveal that a few of these species are not indeed “valid.” Among the currently accepted species, approximately half are recognized human and/or animal pathogens. Manifestations of disease range from cutaneous infection caused by traumatic inoculation of the organism in a normal host to severe pulmonary or central nervous system (CNS) disease in an immunocompromised host (9, 20, 22, 24, 61, 171, 204).

Keywords:Nocardia,genusNocardia,phenotypic,Nocardiaceae,Corynebacteriaceae,
Actinomycetales,
16S rRNA gene,Mycobacterium,taxonomy.


Corresponding author: Tel (903) 877-7685; Fax (903) 877-7652

E-mail: richard.wallace@uthct.edu

 

 
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