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Chemical Communications
Vol.
50, No. 15, 2014; Pages: 1848 50

Detection of single-digit foodborne pathogens with the naked eye using carbon nanotube-based multiple cycle signal amplification

Heng Zhang, Yupeng Shi, Fang Lan, Yi Pan, Yankui Lin, Jingzhang Lv, Zhihao Zhu, Qing Jiang and Changqing Yi

Key Laboratory of Sensing Technology and Biomedical Instruments (Guangdong Province), School of Engineering, Sun Yat-Sen University, Guangzhou 510275, China.

Abstract

A carbon nanotube (CNT)-based multiple cycle signal amplification strategy has been demonstrated for detection of single-digit foodborne pathogens with the naked eye. In the present design, CNTs are used as carriers for loading numerous horseradish peroxidase (HRP) and concanavalin A (ConA) tags, and multiple cycle signal amplification is achieved through the biotinylated anti-HRP antibody and avidin-HRP

Keywords:


 
 
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