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Current Status and Future Scope of Microbial Cellulases
2021, Pages 1-17

Cellulase production using different microbial sources

Sunanda Joshia, Monika Choudharya, Nidhi Srivastavab

Department of Bioscience and Biotechnology, Banasthali University, Banasthali, Rajasthan, India.


Cellulose is an abundant natural biopolymer found on earth as a major component of the plant’s cell wall. Microbial cells can digest hemicellulose, cellulose, and lignin by secreting various hydrolytic and oxidative enzymes. Microorganisms such as actinomycetes, aerobic bacteria, yeasts, and fungi produce cellulase, which breaks down cellulose by hydrolyzing β-1,4-glycoside compounds. Like anaerobic bacteria, aerobic bacteria lack the ability to effectively penetrate into the cellulosic material, contributing to the development of complex cellulosic systems called cellulosomes (multienzyme complexes formed by many cellulolytic microorganisms). Microbial cells have wide applications in diverse fields, constituting a wide class of industrial enzymes. Improving the economies of such processes would result in a cost reduction in the development of cellulase that can be achieved through better bioprocesses and better genetic improvement to yield more of the enzymes. Knowing the significance of cellulase in this chapter is an overview of the spectrum of cellulolytic microbes from around the world.

Keywords: Cellulase, Cellulose, Fermentation, Microorganisms and biofuel.

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