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Current Opinion Biotechnology
Vol. xx, No: xx, 2012, Pages: xx-xx

Systems biology approach to bioremediation

Chakraborty R, Wu CH, Hazen TC

State Key Laboratory of Desert and Oasis Ecology, Xinjiang Institute of Ecology and Geography, Chinese Academy of Sciences, Urumqi 830011, People's Republic of China.

Abstract

Bioremediation has historically been approached as a 'black box' in terms of our fundamental understanding. Thus it succeeds and fails, seldom without a complete understanding of why. Systems biology is an integrated research approach to study complex biological systems, by investigating interactions and networks at the molecular, cellular, community, and ecosystem level. The knowledge of these interactions within individual components is fundamental to understanding the dynamics of the ecosystem under investigation. Understanding and modeling functional microbial community structure and stress responses in environments at all levels have tremendous implications for our fundamental understanding of hydrobiogeochemical processes and the potential for making bioremediation breakthroughs and illuminating the 'black box'.

Keywords:Bioremediation;dynamics of the ecosystem;modeling functional microbial;hydrobiogeochemical processes.


 

 

 
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