Home About us MoEF Contact us Sitemap Tamil Website  
About Envis
Whats New
Microorganisms
Research on Microbes
Database
Bibliography
Publications
Library
E-Resources
Microbiology Experts
Events
Online Submission
Access Statistics

Site Visitors

blog tracking


 
Industrial Crops and Products
Vol. 74, 2015, Pages: 412–416


Phenolic profile and antimicrobial activity of different dietary supplements based on Cochlospermum angolensis Welw

Carla Pereiraa, Lillian Barros, Maria Josť Alves, Liliana Pereira, Celestino Santos-Buelga, Isabel C.F.R. Ferreira

Centro de Investigação de Montanha (CIMO), ESA, Instituto Politécnico de Bragança, Campus de Santa Apolónia, apartado 1172, 5301-855 Bragança, Portugal.

Abstract

Three different formulations (infusion, pills and syrup) of Cochlospermum angolensis were characterized by HPLC–DAD–ESI/MS regarding phenolic composition, and evaluated by their in vitro antimicrobial activity against clinical isolates of multiresistant bacteria. Infusion and pills showed the highest variety of phenolic compounds, with eleven molecules identified. Protocatechuic acid was only present in infusions, being the most abundant compound, while (epi) gallocatechin-O-gallate was the main molecule identified in pills and eucaglobulin/globulusin in syrup. Infusion revealed antimicrobial activity against all the studied bacteria with the exception of Proteus mirabilis whereas the pills revealed activity in Escherichia coli spectrum extended producer of β-lactamases and methicillin-resistant Staphylococcus aureus. In the syrup, there was no antimicrobial activity detected, which is in agreement with its low concentrations of phenolic compounds. None of the formulations inhibited P. mirabilis. Considering the obtained results, C. angolensis infusion can be considered a good source of phenolic compounds as well as a good antimicrobial agent.

Graphical abstract

Keywords: Cochlospermum angolensis; Infusion/pills/syrup; Phenolic compounds; Antimicrobial activity; Clinical isolates.

 
Copyright © 2005 ENVIS Centre ! All rights reserved
This site is optimized for 1024 x 768 screen resolution